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4,107 These findings are further supported by RCTs in older adults demonstrating that dietary weight loss alone leads to a decline in BMD, while control groups maintain stable bone mass

Another shift that can be observed among incident patients is that of the age distribution: the proportion of the three younger age groups increased after 2021, while the two older age groups decreased

Ann Intern Med 141(11):84650

Nonetheless, GLP-1RA is known to affect the intestinal environment and, indeed, changes in the gut microbiota have been linked to GLP-1RAs 26,27,28

For anyone tracking their GLP-1 related energy levels and metabolic markers, butyrate production is one of the most important metrics of gut health that rarely gets discussed outside of specialized research circles