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10 GLP-1R agonists with larger molecular sizes, i.e., the once-weekly albiglutide (HSA-conjugated) and dulaglutide (Fc-conjugated) have a reduced effect on weight-loss in clinical trials compared to liraglutide

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The data reinforce that GLP-1RAs exert cardiovascular benefit through multiple mechanisms beyond fat reduction, with approximately two-thirds of the effect unexplained by changes in body composition

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Detection and analysis of signals of adverse events of memantine based on the US food and drug administration adverse event reporting system