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I do not take a GLP-1 myself but have worked with hundreds of people who have
doi: 10.5694/mja2.52170 [DOI] [PubMed] [Google Scholar] 76.Wilding JPH, Batterham RL, Calanna S, et al
An Endocrine Society study presented at ENDO 2025 found that anti-obesity medications, including semaglutide and tirzepatide, can normalize testosterone levels in men
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The most potent undecapeptide contains two substituted biphenylalanines at the C-terminus and showed surprisingly high potency as a truncated GLP-1 analog (200-fold decrease)
A once-daily oral GLP-1 with comparable efficacy could meaningfully expand who actually stays on therapy long enough to see benefit
