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Tirzepatide has shown greater average weight loss in head-to-head trials, but semaglutide is the longer-established option with years of real-world data and proven results

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[DOI] [PMC free article] [PubMed] [Google Scholar] 75.Brierley DI, Holt MK, Singh A, de Araujo A, McDougle M, Vergara M, et al