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However, the absence of prospective short- and long-term outcome data underscores the need for systematic investigation to define optimal timing, safety parameters, and oncologic efficacy of weight-loss interventions in this high-risk population.

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The 2.6 billion manufacturing investment complements the recent US manufacturing expansion for its next potential blockbuster obesity treatment orforglipron.

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Weight loss on semaglutide doesn't happen overnight, but most patients notice meaningful changes between weeks 4 and 8 of treatment