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Evidence that some antidiabetic agents improve NAFLD/NASH with fibrosis in patients with T2DM is emerging

Understanding semaglutide fatigue is particularly important in this population, as fatigue can reduce motivation to maintain adequate fluid intake

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Although the impact of GLP-1RAs on pancreatic cancer risk remains controversial, emerging evidence suggests that chronic low-grade inflammation and proliferative changes may constitute key pathophysiological mechanisms underlying pancreatic cancer development in patients receiving GLP-1RA therapy [8]

It also appears to reduce systemic inflammation, which is now understood to be a significant driver of treatmentresistant depression in a meaningful subset of patients

Speak with your healthcare provider if youre dealing with constipation thats unbearable or interfering with daily life, as you might need a medication adjustment