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Herein, we successfully switched a patient with acromegaly from a dipeptidyl peptidase-4 (DPP-4) inhibitor to a glucagon-like peptide-1 (GLP-1) analog due to pasireotide-induced deterioration of glycemic control, and we examined the underlying mechanism for glycemic control

Average weight loss (clinical trials)
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Compared to semaglutide alone, the combination resulted in significantly greater weight loss, better body composition, and reductions in visceral fat and inflammation
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HAP were obtained during open-heart surgery from adult patients with severe coronary heart disease
