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Evidence supports even simple activities like: Higher daily step counts Resistance training to preserve lean mass Maintaining muscle to support metabolic health (muscle burns more resting calories) Optimize Medication Dose Maximum average weight loss in GLP-1/GIP clinical trials occurred at higher doses

20 This creates a bifurcated market where the patent holder is constrained by supply chain limitations, while competitors are unleashed to fill the void

According to one clinical trial, most patients lost 10-15% or more of body weight by week 68

However the change does not apply to overweight patients with a BMI of less than 30kg/m using Wegovy for weight management

Rybelsus is currently the only oral semaglutide drug on the market
