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GLP-1 receptor agonists (GLP-1 RAs) with exenatide b.i.d

Among the marketed large molecule injectable GLP-1 agonists, semaglutide, apart from weight-loss, is being studied for kidney disease and tirzepatide (a dual GLP-1 and GIP receptor agonist) is being evaluated for sleep apnea in Ph 3 clinical trials

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Allulose is a rare sugar that may modestly support GLP-1 secretion through gut hormone pathways, but dietary changes alone rarely match the effect of prescription GLP-1 therapy