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Eli Lilly and Company has announced topline results from the SURMOUNT-5 phase 3b open-label randomised clinical trial that found Zepbound (tirzepatide) provided a 47% greater relative weight loss vs
Hepatic Effects: Semaglutide has been shown to reduce liver fat content in patients with non-alcoholic fatty liver disease (NAFLD), possibly through improvements in insulin sensitivity and lipid metabolism
Future research is crucial to investigate whether a washout period for GLP-1 agonists before CLN is needed to reduce the risk of AC, if such a risk exists.
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