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Objective: To evaluate the efficacy and safety of semaglutide combined with metformin in treating type 2 diabetes mellitus (T2DM) patients who are overweight or obese

Due to the bodys natural tendency to restore its former weight, many people regain their lost weight when they stop using GLP-1 drugs.

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When oxidative demand approaches the regenerative capacity of nicotinamide adenine dinucleotide (NAD)/ nicotinamide adenine dinucleotide phosphate (NADPH

Limitations include the post hoc design, lack of multiplicity adjustment, and incomplete capture of background therapy changes

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