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Main text Within this review, we provide an overview of the intricate interplay between chronic inflammation of the adipose tissue and the hypothalamus and the development of obesity

The class of drugs, which includes Novo Nordisks Ozempic and Wegovy, are associated with the risk of gastrointestinal adverse events when used for weight loss, finds a study published Thursday in JAMA.
The excess risk of acute pancreatitis was more pronounced during the early phase of follow-up (first 6 months)

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The incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic peptide are secreted by enteroendocrine cells and augment glucose-induced insulin secretion in response to food ingestion in a glucose-dependent manner

Will any of the 50+ clinical-stage assets currently in development meet these unmet needs?