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GLP-1 RAs: Clinical Primer GLP-1 is a regulatory hormone derived from the proglucagon gene and secreted in response to food consumption

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For context, Medicaid spending on GLP-1 drugs in Pennsylvania was $1.3bn in 2025 - a whopping twice as much as the previous year

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For a deeper dive into related GLP-1 side effects, read our guide to why GLP-1 medications cause GI issues
doi: 10.1038/ijo.2011.158 [DOI] [PMC free article] [PubMed] [Google Scholar] 89