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An invited commentary on this study, also published in JAMA Ophthalmology, challenges the idea that the increased risk of NAION among semaglutide users resulted directly from the medication

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Some preclinical studies have found that the GLP-1 hormone may help prevent the buildup of tau tangles and amyloid plaques, which are associated with Alzheimers disease, but researchers stressed the need for more data

2021;16(1) doi: 10.1371/journal.pone.0244847

it also contributes to your overall health and resilience

This coordinated engagement across the pancreas, brain, gut, liver, and adipose tissue underlies the mechanistic rationale for dual GLP-1/GIP receptor agonists, and explains why they have been described as super GLP-1RAs, reflecting genuine potentiation of GLP-1 action by GIP receptor agonist co-activation