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Body weight, a key secondary endpoint, decreased by 11.5% to 16.8% with retatrutide and by 2.5% with placebo

A structured narrative literature review was conducted by five authors using MEDLINE/PubMed as the primary database, covering publications in English from January 2005 to January 2025

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"In Indonesia, we are facing a critical rise in obesity, which frequently acts as a gateway to other life-threatening conditions such as diabetes and heart disease." "For many, lifestyle changes alone are not enough and they deserve access to comprehensive medical support," she stated

She explained that these medications act on brain pathways to regulate weight, so once you stop taking them, the benefits also stop

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