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Blockade of IL-10 with a neutralizing antibody fully inhibited exenatide-induced -endorphin expression both in vitro and in vivo, effectively abolishing its mechanical antiallodynic effects in neuropathic rats [63]

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Meet our doctors Last reviewed: 19 Jun 2026 Sources Mounjaro KwikPen 10mg solution for injection in pre-filled pen SmPC, emc [accessed 25 May 2026] Once-Weekly Semaglutide in Adults with Overweight or Obesity, The New England Journal of Medicine (NEJM) [accessed 25 May 2026] Ozempic SmPC, emc [accessed 25 May 2026] Rybelsus 3 mg, emc [accessed 25 May 2026] Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes, NEJM [accessed 25 May 2026]