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The mechanism involves several pathways: slowing gastric emptying (which helps people feel full longer), reducing appetite signals in the brain, and improving how the body processes glucose
Advanced Type 2 diabetes with severe beta cell dysfunction: Patients who have had diabetes for decades with minimal remaining insulin production may see less glucose benefit (though weight loss still occurs)
Human gut microbiome: hopes, threats and promises
PMID: 34 KaracabeyliDLacailleD
Look AHEAD Research Group
doi: 10.1016/S0140-6736(19)31149-3 [DOI] [PubMed] [Google Scholar] 255
