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Lancet (london, England) 374:3947

Clinical trials show Mounjaro produces the highest average weight loss (15-25% of body weight) compared to alternatives 7

For pharma, this opened a new channel beyond the doctors office

Understanding your genetic predispositions allows your provider to personalize your starting dose, escalation schedule, and combination therapy options for faster, more sustainable results

Participants were randomly assigned to receive either 120 mg of orlistat or a placebo three times daily, in conjunction with a hypocaloric diet during the first year, followed by a weight maintenance diet in the second year

Participants in clinical trials experienced an average body weight loss of 12.4%
