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Increased risk of low blood sugar, particularly if used along with insulin or an insulin secretagogue

271 The activation of AMPK has been shown to inhibit NF-B pathway activation

The review included a comprehensive search of peer-reviewed articles published between January 2010 and November 2024 conducted using the PubMed and Medline databases, supplemented by the inclusion of relevant studies from earlier periods when clinically justified

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Hutton B, Salanti G, Caldwell DM, Chaimani A, Schmid CH, Cameron C, Ioannidis JP, Straus S, Thorlund K, Jansen JP, Mulrow C, Catal-Lpez F, Gtzsche PC, Dickersin K, Boutron I, Altman DG, Moher D
