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It should not be used by people with a history of pancreatitis, medullary thyroid cancer, or diabetic retinopathy (a diabetes-related eye disease that damages the blood vessels in the retina)

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Impact of GLP-1 receptor agonists on major gastrointestinal disorders for type 2 diabetes mellitus: a mixed treatment comparison meta-analysis

Wadden, S

It also targets the brain's appetite center to reduce hunger signals, supporting effective weight loss