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GLP-1 medications are not appropriate for all individuals and require clinical evaluation

Miras AD, Prez-Pevida B, Aldhwayan M, Kamocka A, McGlone ER, Al-Najim W, Chahal H, Batterham RL, McGowan B, Khan O, Greener V, Ahmed AR, Petrie A, Scholtz S, Bloom SR, Tan TM

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In conclusion, ESSENCE establishes semaglutide as a cornerstone therapy for MASH with F2-F3 fibrosis in metabolically high-risk patients, providing robust histologic improvement, substantial weight loss, and broad cardiometabolic benefit

The device delivers stimulation for 1 minute each day and is recharged during 10 minutes each week wirelessly via a necklace (schematic below)