why haven't i lost weight on tirzepatide ✨ patient — 6 months later🔥 40 pounds down and feeling stronger than ever 🙌 Thanks to healthy habits, consistency, and exercise, this patient didn't just lose — they were Why Am I Not Losing

J., & Stucky, N

As with other existing GLP-1 RA agents, major adverse effects in each SURPASS trial were predominantly GI-related, including nausea, vomiting, diarrhea, and decreased appetite

Cause: the weight loss, not a toxic effect on the hair follicle

Funding The study and all support for the manuscript, including the journals Rapid Service Fee, were funded by Eli Lilly and Company, Indianapolis, USA

Tirzepatide works against all of these trends simultaneously

But it bears mentioning because patients switching from an MAO inhibitor need a minimum 14-day washout period before starting bupropion, and tirzepatide should not be initiated during this transition period when neurochemistry is already in flux