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24 hours after taking certain diabetes medications (like insulin or sulfonylureas, if youre using them together with GLP-1s) Between meals, when blood sugar naturally dips During or after exercise, especially if you havent eaten enough beforehand After dose changes, as your body adapts to stronger appetite-suppressing effects During rapid weight loss or dietary changes, when your energy intake is lower than usual Whos at higher risk

If you are treating obesity, the FDA indication, expected average weight loss, and long-term sustainability matter most

In this regard, the role of the GCGR in mediating lipolysis is controversial

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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Mody R., Huang Q., Yu M., Zhao R., Patel H., Grabner M., Land L.F

The generic medications are expected to be less expensive than Mounjaro and Zepbound