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Research suggests roughly 30% of weight lost on GLP-1 therapy comes from lean mass, with significant variability between studies. With adequate protein intake and consistent resistance training, that proportion can be reduced

Diet-related disparities: understanding the problem and accelerating solutions

10.1038/nrdp.2017.13 [DOI] [PubMed] [Google Scholar] 55.Kalia LV, Lang AE

30 Furthermore, metabolic conditions such as iron deficiency can alter progenitor cell fate, favoring adipogenesis over osteogenesis, underscoring the sensitivity of these developmental processes to energetic signals

Additionally, the loss of fatty acids compromises the skin barrier, resulting in dryness

At a White House event Thursday, President Trump announced deals with drugmakers Novo Nordisk and Eli Lilly to offer their popular GLP-1 obesity and diabetes drugs at lower prices for some Americans, namely some on Medicare and Medicaid plans