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According to researchers from Johns Hopkins, women who take GLP-1 RAs lose an average of 11% of their starting weight after 43 weeks of treatment

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Hydration is key and can help prevent nausea, constipation, and dehydration

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Taylor K et al

We also found that GLP-1R interacted with the PKA/CREB pathway and that liraglutide could activate PKA/CREB signals, thereby inhibiting the expression of inflammation-related proteins