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So the logic seems obvious

Real-world observational data from Truveta (2024), analysing over 18,000 patients, which found greater 12-month weight loss with tirzepatide in clinical practice [4]

Baseline metabolic status also matters

Appetite suppression becomes more noticeable
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SGLT2 inhibitors, commonly prescribed for type 2 diabetes, substantially increase the risk of genital mycotic infections due to their mechanism of increasing urinary glucose excretion