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For many, injections are a barrier to regular use, whether due to fear of needles or the hassle of remembering to administer the medication at specific times

While it is effective, some people report heart palpitations while taking it

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If that describes you, the front thigh is a reliable primary site, and your provider can help you assess which works best for your body composition

To get the most out of spironolactone, it's essential to collaborate closely with your doctor, use reliable contraception, and stay on top of routine lab work

As mentioned, the majority of the research on GLP-1s for PCOS has been in folks who have a higher weight, so its not clear how much of the benefits would translate to people with the condition who fall at lower weights, nor is it known whether the latter folks can safely take these drugs