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Never stop or reduce your GLP-1 medication without medical guidance, even if dizziness occurs

Practical pharmacist checklist before changing therapy: Verify renal clearance, percent renal excretion, protein binding, and Vd in the monograph

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Many patients continue to lose weight over several months

Over time, this causes immense strain on the kidneys and body as a whole, which shows up through symptoms like frequent urination, fatigue, increased thirst and hunger, and slow-healing sores along with increased infections

But at the doses used, the net effect on blood sugar is positive because the GLP-1 and GIP activity dominates, and the glucagon activation primarily drives fat burning rather than glucose release