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GLP-1 medications slow gastric emptying, which can lead to constipation

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Glucagon-like peptide-1(7-37)/(7-36)amide is a new incretin

In DAPA-CKD, among 4,304 participants (67.5% with type 2 diabetes mellitus and 15.3% with prediabetes at baseline), the mean eGFR was 43.1 mL/min/1.73 m and the median UACR was 949 mg/g [47,52]

Studies find a body weight loss of 1 to 2 percent per month typical on GLP-1, with up to about 22 percent at one year in some trials
