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The protective effects of HO-1 are said to be mediated by one of its productscarbon monoxide (CO)

presenting studies with difficulties regarding study start-up and inclusion

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conducted a subgroup analysis of the Qatar study, an open-label, randomized controlled trial (62), and compared the peripheral neurological outcomes in patients receiving a combination of exenatide (2 mg/week) and pioglitazone (30 mg/day) and those receiving glargine plus aspart insulin (58)