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Other side effects may include fatigue and headache

There are some important contraindications for taking GLP-1 medications: a severe allergic reaction to a GLP-1 medication in the past a history of pancreatitis pregnancy or breastfeeding a history of medullary thyroid cancer or multiple endocrine neoplasia type 2 in yourself or an immediate family member Finally, cost and access need to be considered

Are the benefits real

But for medications at the price point of GLP-1 drugs, they're a normal part of the process

These are the most common side effects and often improve over time as your body adjusts to the medication

Both treatment approaches resulted in a mean weight loss at 52 weeks, with oral semaglutide treatment resulting in a mean weight loss from baseline of 3.8 kg and 4.7 kg in the treatment-policy estimand and trial-product estimand analyses, respectively