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Description
Glucagon agonism in the treatment of metabolic diseases including type 2 diabetes mellitus and obesity
Methods This is a narrative review based on a literature search in the PubMed database up to February 26, 2021
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On the basis of results of the most recent CVOTs (DAPA-HF, DAPA-CKD, EMPEROR-R), the FDA has approved dapagliflozin (2020) and empagliflozin (2021) to reduce risk for CV death and HF hospitalization in adults with HF and reduced ejection fraction regardless of whether they have diabetes [24, 25]
Other data suggest that more than 80% of people regain at least a quarter of the weight they lost within a year of stopping
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