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In this context, even moderate increases in oxidative demand can favor conditions that increase mitochondrial electron leakage and ROS formation, particularly when respiratory reserve and redox-buffering capacity are reduced

10.1001/jama.287.19.2563 [EL 4

Suffice it to say, that the legislature and AGs combined aggressive approach to countering fentanyl use in Kentucky will continue to lead to increased drug charges, mandatory minimum sentences, and long-term penalties for all fentanyl-related charges throughout the state