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[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Zhu C, Xu R, Li Y, Andrade M & Yin DP Gastric bypass prevents diabetes in genetically modified mice and chemically induced diabetic mice
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The increased risk of amputation seen in the large, long-term Canagliflozin Cardiovascular Assessment Study (CANVAS) trial for canagliflozin, and select observational studies, merits further research but overall, there is currently no consistent evidence of SGLT2i exposure and increased risk of amputation

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5.0%), and heavy (more than five times/month) current cannabis users (3.3%)
