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Phentermine increases heart rate and blood pressure through sympathomimetic activity, while GLP-1 agonists have shown mixed cardiovascular effectsbenefits in diabetic populations but potential concerns in certain patient subgroups, particularly those with a history of thyroid cancer or multiple endocrine neoplasia

"If they're not providing you that offer of patient counseling or you're calling into that pharmacy and they don't allow you to, you know, be progressed to a pharmacist where you can ask questions, that would be something that I would call a red flag." She says prices that are too low and pharmacies that don't ask for a prescription should also trigger alarm bells

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Long-term effectiveness and safety of liraglutide in clinical practice

To summarize these mechanisms and their corresponding efficacy with GLP-1RAs or GLP-1, GLP-1RAs show the endothelial protective properties and thus owe to modulating vascular tone and maintaining endothelial barrier integrity, as well as the anti-adhesive and anti-thrombotic actions