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Cardiovascular Effects Dose-dependent increases in heart rate were observed with retatrutide: Heart rate increases peaked at approximately 24 weeks Gradually declined thereafter while remaining elevated above baseline This pattern is similar to that observed with other GLP-1 receptor agonists[4] The clinical significance of these heart rate changes requires further evaluation in larger and longer-term studies

To reduce the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes with known heart disease

People taking GLP-1 drugs had fewer alcohol-related hospitalizations than people taking standard drugs for alcohol use disorder.

Learn what to expect after first dose of Ozempic, the common effects, tips, and how to ease symptoms

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