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doi:10.3389/fphar.2019.01568 75
evaluated retatrutide a once-weekly injectable agent targeting GLP-1, GIP, and glucagon receptors simultaneously across multiple doses in adults with obesity or overweight without type 2 diabetes

Losing weight at a steady pace through sensible dose titration lowers the risk compared with pushing for the fastest possible results
47 In addition to its direct effects on gallbladder contraction and sphincter of Oddi relaxation, CCK is involved in molecular and neuronal pathways that regulate both gallbladder function and satiety

However, there are no targeted drugs specifically designed to treat NAFLD
