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[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Beck RW, Connor CG, Mullen DM, Wesley DM, Bergenstal RM

Approved in 1964 for the management of hypertension, propranolol is now used for a wide range of cardiovascular diseases, including ischemic heart disease, angina pectoris, arrhythmias, and myocardial infarction, as well as non cardiovascular conditions, including migraine, tremors and anxiety

These medicines mimic the action of a naturally occurring hormone called GLP-1, which is produced in the intestines in response to food intake

55 Despite the significantly shortened length of the peptide, 9 showed a high potency (EC 50 = 0.087 nM) compared to GLP-1 (0.034 nM) and a longer pharmacokinetic half-life

When healthy behaviors become part of a routine rather than a temporary program, long-term success becomes more achievable