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What you do get with Peak though is clinical oversight: before each refill, a medical professional reviews a short check-in on how your side effects and results are going, and can hold or adjust your dose instead of automatically moving you up

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This phenomenon may be the result of its unbalanced dual agonistic effect, favoring GIPR over GLP-1R activity [7], because dose escalation of selective GLP-1R agonists induces undesirable gastrointestinal effects