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What the preclinical signal tells us One of the clearest historical preclinical signals comes from a rat study indexed in PubMed

The main ones are vitamins C and K
These studies have shown that GLP-1 agonists can reduce liver fat and inflammation, which are critical factors in MASH progression5
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Similarly, Jason was prescribed GLP-1s to treat diabetes

This interaction reduces appetite, helping individuals feel fuller for extended periods and decreasing overall caloric intake
