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3 Add-on therapy: Leukotriene receptor antagonist (montelukast) for refractory cases
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Studies in animal models suggest that TMAO may be atherogenic and prothrombotic
It increases insulin release in response to meals, decreases glucagon secretion (which raises blood sugar levels), and delays gastric emptying, leading to increased feelings of fullness and reduced food intake
A common implementation: eating window from 11am to 7pm, or 12pm to 8pm
This can occur even when healthy eating and exercise habits continue
