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Serious side effects requiring immediate medical attention: pancreatitis (severe, persistent abdominal pain), kidney complications from dehydration caused by nausea, vomiting, or diarrhea, acute gallbladder disease, diabetic retinopathy changes in patients with type 2 diabetes, severe gastrointestinal disease, hypoglycemia when combined with insulin or sulfonylureas, increasing heart rate, and worsening depression or suicidal ideation

These tend to be places where you can easily access the subcutaneous (fatty areas) under the skin and the needle will not come too close to muscle or bone

Over 1,800 physicians responded, providing valuable insight into how they are navigating the use of GLP-1 agonists

Current utilization patterns of glucagon-like peptide-1 receptor agonists: report [Internet]

Asian J

Interestingly, there have been a few reports suggesting a direct interaction between metformin and the incretin axis [79]