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Accessed 16 July 2021 158.Diabetes UK (2021) Diabetes when youre unwell

Future clinical studies should determine which patient groups should be targeted as potential candidates for the symptomatic and/or neuroprotective effects of GLP-1RAs, to find out, whether combinations of GLP-1RA with other classes of drugs can further enhance their effectiveness, and evaluate their long-term effect on the course of the disease and side effects

Lau J, Bloch P, Schffer L, Pettersson I, Spetzler J, Kofoed J, Madsen K, Knudsen LB, McGuire J, Steensgaard DB, Strauss HM, Gram DX, Knudsen SM, Nielsen FS, Thygesen P, Reedtz-Runge S, Kruse T

Furthermore, the study showed that AP GLP-1R neurons were not required for reducing food intake, while NTS GLP-1R neurons could evoke satiation without aversive effects, highlighting future directions for a non-aversive GLP-1R drug [74] (Fig

Accurate, though weight loss is modest compared to GLP-1 RAs (typically 24 kg)

Oral treatments could help bring younger patients into the category who may never have considered injections