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Description
Hepatology 2015;62:1417-1432
Two other brand-name semaglutide drugs, Ozempic and Rybelsus, are not approved for weight loss but are often prescribed off-label for that use
It avoids first-pass liver metabolism, which means lower risk of blood clots and a better lipid profile compared to oral estrogen
Interestingly, the degree of weight loss associated with GLP-1 RAs appears to be less noticeable in individuals with T2D
Also promising research to show an increase in GLP-1 production
Observational studies were assessed through ROBINS-I (Sterne et al
