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95% CI 1.84 to 0.38

Despite being discovered first, it received less clinical attention for decades because early research suggested that GIP signaling was impaired in type 2 diabetes, making it seem like an unlikely therapeutic target

95% CI 2.27, 1.53), SGLT2is/metformin (WMD: 1.9%

Cardiovascular disease is a common complication of metabolic dysfunction, making these medications valuable in addressing long-term health risks
