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The treatment of obese adults with retatrutide resulted in a mean weight reduction of 24.2% after 48 weeks, and was associated with improvements in cardiometabolic measures (exploratory endpoints) including systolic and diastolic blood pressure, levels of glycated hemoglobin, fasting glucose, insulin, and lipids (141)

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While GLP-1 agonists primarily affect the pancreas and gut to regulate insulin secretion and gastric emptying, cagrilintide acts on the brain to suppress appetite and food intake

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Typically given through weekly injections, changes to diet and medication are also combined with this medication

any compounded option is an individualized clinical decision made by your provider for a specific patient, never marketed as identical to or interchangeable with the brand