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The mitochondrial permeability transition pore (MPTP) is activated by elevated ROS and Ca + levels, which result in the release of cytochrome c and the start of cell death pathways

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J Vestib Res 26:409415 Lucieer F, Vonk P, Guinand N, Stokroos R, Kingma H, van de Berg R (2016) Bilateral vestibular hypofunction: insights in etiologies, clinical subtypes, and diagnostics
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