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Many GLP-1s are already FDA approved and physicians can legally prescribe them off-label for any use

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( 10.1016/j.molmet.2022.101641) [DOI] [PMC free article] [PubMed] [Google Scholar] Merchenthaler I Lane M & Shughrue P

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A qualified provider must weigh individual risk factors, particularly if you have a history of hypertension, heart disease, or metabolic syndrome

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For comprehensive overview of all options, check our comparison of weight loss medications in 2026

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Youre more likely to be a good candidate if you have a BMI of 27 with associated weight-related health issues or a BMI of 30 or higher

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