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Due to the well-known high glucose-mediated epigenetic changes, the potential role on DNA methylation of genes involved in neuroprotection and epigenetic modulators of neuronal growth (miRNA 34a), apoptosis (miRNA 212) and differentiation (miRNA 29c) was also investigated

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Clinical trial results showed that participants experienced 15% to 18% weight loss during the trials

Kapur J, Long L, Dixon-Salazar T

The healthcare provider may need to assess for alternative causes including hypothyroidism, electrolyte abnormalities, or other medications contributing to reduced bowel motility