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doi: 10.3389/fmed.2021.777861 23 HoongCWSChuaMWJ

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Grade C = Supportive evidence from poorly controlled or uncontrolled studies

Doctors told CNN that they are receiving more and more reports of gastrointestinal issues in patients who have taken the following similar diabetes/weight loss drugs: As the popularity of the drugs has soared, the US Food and Drug Administration told CNN it had received reports of gastroparesis with semaglutide and liraglutide, some of which documented the adverse event as not recovered after discontinuation of the respective product at the time of the report. (Novos Ozempic and a similar drug, Wegovy, utilize the same medication semaglutide

That dual mechanism appears to produce stronger appetite suppression and greater fat mass reduction in clinical trials